Between June 2020 and January 2021, a comparison of UVC disinfection versus enhanced liquid disinfection practices on high-touch surfaces was done. The settings included a sports stadium in Australia and 5 airports and 6 retail/pharmacy locations in the USA states and Canada. A total of 111 high touch surfaces were sampled, and over 300 swabs were obtained to compare enhanced liquid disinfection practices to automated UVC disinfection on the same surfaces. The results from this study indicate that the use of an automated UVC device will significantly decrease bacterial colonization on high-touch surfaces in retail keypads and public touch screen devices.