The menopausal transition is a critical period that necessitates a comprehensive approach to health, often extending beyond the management of hormonal shifts and vasomotor symptoms. Menopause can impact multiple organ systems, requiring clinicians to employ a multi-systems approach. Samuel Peters will explore the full spectrum of menopausal changes, including alterations in bone density, cardiovascular function, cognitive health, and skin integrity and review key herbal ingredients, drawing from both traditional use and scientific research, to support women during the perimenopausal and menopausal phases.