The Great Plains Tribal Leaders Health Board and Great Plains Tribal Epidemiology Center Grant Management Toolkit Roadmap & Glossary is a practical guide designed to help organizations and tribes navigate the full grant lifecycle. It outlines key steps from pre-application readiness and identifying funding opportunities to preparing competitive applications, launching awarded projects, managing grants throughout the project period, and completing closeout requirements. Across these phases, the roadmap outlines essential organizational planning, staffing, budgeting, reporting, partnerships, evaluation, and sustainability activities, and identifies related templates, sample documents, and technical assistance resources. Overall, the toolkit serves as a structured framework to strengthen grant readiness, improve administrative capacity, and support successful funding implementation and management.