Sessions
Sheep as large animals models of human health and cardiovascular disease
3:55 PM - 4:45 PM Fri
Chris Charles performs pre-clinical physiology studies aimed at elucidating the role of novel hormones in controlling blood pressure, salt and water balance and heart function both in normal physiology and heart disease.
Large animal models, sheep in Christchurch and pigs in Singapore, model ischaemia reperfusion injury, myocardial infarction, pacing model of heart failure and HFPEF.
New knowledge gained from these physiological studies not only increases our understanding of how the heart, hormones and nerves interact but underpins the search for novel therapeutic agents for the treatment of lethal cardiovascular diseases.