The lab is focused on following different research areas: 1. Role of interferon signaling in controlling GVHD. 2. Graft engineering using molecular computing cascades to a) achieve depletion of narrow T cell population (e.g. naïve donor T cells) for prevention of GVHD and to b) redirect effector cells. 3. Assessment of bone marrow (BM) from cadaveric donors (CD) as novel source of hematopoietic stem cells (HSC) for clinical transplantation using in vitro and in vivo models.